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dc.contributor.authorRabbani, Khondkar Ayaz
dc.date.accessioned2023-12-04T08:39:24Z
dc.date.available2023-12-04T08:39:24Z
dc.date.issued2017-07-04
dc.identifier.citationAssociations of fats and carbohydrate intake with cardiovascular disease and mortality in 18 countries from five continents (PURE): a prospective cohort study M Dehghan, A Mente, X Zhang, S Swaminathan, W Li… - The Lancet, 2017en_US
dc.identifier.urihttp://ar.iub.edu.bd/handle/11348/837
dc.identifier.urihttps://doi.org/10.1016/S0140-6736(17)32252-3
dc.descriptionThe Prospective Urban Rural Epidemiology (PURE) study is a large, epidemiological cohort study of individuals aged 35–70 years (enrolled between Jan 1, 2003, and March 31, 2013) in 18 countries with a median follow-up of 7·4 years (IQR 5·3–9·3). Dietary intake of 135 335 individuals was recorded using validated food frequency questionnaires. The primary outcomes were total mortality and major cardiovascular events (fatal cardiovascular disease, non-fatal myocardial infarction, stroke, and heart failure). Secondary outcomes were all myocardial infarctions, stroke, cardiovascular disease mortality, and non-cardiovascular disease mortality. Participants were categorised into quintiles of nutrient intake (carbohydrate, fats, and protein) based on percentage of energy provided by nutrients. We assessed the associations between consumption of carbohydrate, total fat, and each type of fat with cardiovascular disease and total mortality. We calculated hazard ratios (HRs) using a multivariable Cox frailty model with random intercepts to account for centre clustering.en_US
dc.description.abstractThe relationship between macronutrients and cardiovascular disease and mortality is controversial. Most available data are from European and North American populations where nutrition excess is more likely, so their applicability to other populations is unclear.en_US
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.titleAssociations of fats and carbohydrate intake with cardiovascular disease and mortality in 18 countries from five continents (PURE): a prospective cohort studyen_US
dc.typeArticleen_US


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